HAVCR2
hepatitis A virus cellular receptor 2
HAVcr-2, KIM-3, TIM3, TIMD-3, TIMD3, Tim-3
Human HAVCR2 (84868), Mouse Havcr2 (171285), Rat Havcr2 (363578), dog HAVCR2 (479318), domestic cat HAVCR2 (101089981), cow HAVCR2 (768047), sheep HAVCR2 (101112135)
- Human(84868) Summary: The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]
- Mouse(171285) hepatitis A virus cellular receptor 2
- Rat(363578) hepatitis A virus cellular receptor 2
- dog(479318) hepatitis A virus cellular receptor 2
- domestic cat(101089981) hepatitis A virus cellular receptor 2
- cow(768047) hepatitis A virus cellular receptor 2
- sheep(101112135) hepatitis A virus cellular receptor 2
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Anti-TIM3/HAVCR2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
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