GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
Synonyms:
GluN2C, NMDAR2C, NR2C
Species:
Human GRIN2C (2905), Mouse Grin2c (14813), Rat Grin2c (24411), sheep GRIN2C (101102915), domestic guinea pig Grin2c (100721967), naked mole-rat Grin2c (101698922), chicken GRIN2C (431090), dog GRIN2C (483302), cow GRIN2C (535158), domestic cat GRIN2C (101091740)
UniProtKB ID:
Gene ID:
- Human(2905) Summary: This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of ionotropic glutamate receptor. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
- Mouse(14813) glutamate receptor, ionotropic, NMDA2C (epsilon 3)
- Rat(24411) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
- sheep(101102915) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
- domestic guinea pig(100721967) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
- naked mole-rat(101698922) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
- chicken(431090) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
- dog(483302) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
- cow(535158) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
- domestic cat(101091740) glutamate receptor, ionotropic, N-methyl D-aspartate 2C
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Small Molecule - Agonist
Product Number
Description
Species
Small Molecule - Allosteric Modulator
Product Number
Description
Species
Ketamine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-NMDAR2C Antibody, also recognizes NMDAR2A and 2B, Chemicon®, from rabbit,
Species Reactivity
rat
Application
immunoprecipitation (IP)
western blot
western blot
Anti-Glutamate Receptor NMDAR2C (NR2C) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Small Molecule - Blocker
Product Number
Description
Species
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Small Molecule - Inhibitor
Product Number
Description
Species
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human