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Merck

GCHFR

GTP cyclohydrolase I feedback regulator

Synonyms:
GFRP, HsT16933, P35
Species:
Human GCHFR (2644), Mouse Gchfr (320415), Rat Gchfr (171128), Zebrafish gchfr (393735), chicken GCHFR (423003), dog GCHFR (487498), cow GCHFR (617650), domestic cat GCHFR (101088493), sheep GCHFR (101110240), domestic guinea pig Gchfr (100717119)
UniProtKB ID:
P30047, B2R4L6, Q2M1Q2, Q99749
Gene ID:
  • Human(2644) Summary: GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide. [provided by RefSeq, Jul 2008]
  • Mouse(320415) GTP cyclohydrolase I feedback regulator
  • Rat(171128) GTP cyclohydrolase I feedback regulator
  • Zebrafish(393735) GTP cyclohydrolase I feedback regulator
  • chicken(423003) GTP cyclohydrolase I feedback regulator
  • dog(487498) GTP cyclohydrolase I feedback regulator
  • cow(617650) GTP cyclohydrolase I feedback regulator
  • domestic cat(101088493) GTP cyclohydrolase I feedback regulator
  • sheep(101110240) GTP cyclohydrolase I feedback regulator
  • domestic guinea pig(100717119) GTP cyclohydrolase I feedback regulator

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