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Merck

CDC25A

cell division cycle 25A

Synonyms:
CDC25A2
Species:
UniProtKB ID:
Gene ID:
  • Human(993) Summary: CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(12530) cell division cycle 25A
  • Rat(171102) cell division cycle 25A
  • chicken(420375) cell division cycle 25 homolog A (S. pombe)
  • cow(520188) cell division cycle 25 homolog A (S. pombe)
  • Horse(100064223) cell division cycle 25 homolog A (S. pombe)
  • domestic cat(101098445) cell division cycle 25 homolog A (S. pombe)
  • dog(484780) cell division cycle 25 homolog A (S. pombe)
  • sheep(101113178) cell division cycle 25 homolog A (S. pombe)
  • domestic guinea pig(100721008) cell division cycle 25A
  • naked mole-rat(101699133) cell division cycle 25A

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Phospho-CDC25A-S76 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Monoclonal Anti-CDC25A antibody produced in mouse, clone 3D5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
proximity ligation assay

western blot
Anti-CDC25A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence

Small Molecule - Inhibitor

Product Number
Description
Species
NSC 95397, ≥97% (HPLC),
Species
human