CASP14
caspase 14, apoptosis-related cysteine peptidase
Synonyms:
Species:
Human CASP14 (23581), Mouse Casp14 (12365), Rat Casp14 (299587), naked mole-rat Casp14 (101720095), domestic guinea pig Casp14 (100715745), sheep CASP14 (101120827), chicken CASP14 (776274), cow CASP14 (517658), domestic cat CASP14 (101099027), dog CASP14 (610460)
UniProtKB ID:
Gene ID:
- Human(23581) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. [provided by RefSeq, Jul 2008]
- Mouse(12365) caspase 14
- Rat(299587) caspase 14
- naked mole-rat(101720095) caspase 14, apoptosis-related cysteine peptidase
- domestic guinea pig(100715745) caspase 14, apoptosis-related cysteine peptidase
- sheep(101120827) caspase 14, apoptosis-related cysteine peptidase
- chicken(776274) caspase 14, apoptosis-related cysteine peptidase
- cow(517658) caspase 14, apoptosis-related cysteine peptidase
- domestic cat(101099027) caspase 14, apoptosis-related cysteine peptidase
- dog(610460) caspase 14, apoptosis-related cysteine peptidase
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.