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Merck

BAIAP2L1

BAI1-associated protein 2-like 1

Synonyms:
IRTKS
Species:
Human BAIAP2L1 (55971), Mouse Baiap2l1 (66898), Rat Baiap2l1 (304282), chicken BAIAP2L1 (416437), dog BAIAP2L1 (479748), cow BAIAP2L1 (615412), domestic cat BAIAP2L1 (101098023), naked mole-rat Baiap2l1 (101719088), domestic guinea pig Baiap2l1 (100724572), sheep BAIAP2L1 (101114328)
UniProtKB ID:
Q9UHR4, A4D268, Q75L21, Q75L22, Q96CV4, Q9H5F5, Q9Y2M8
Gene ID:
  • Human(55971) Summary: This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation. [provided by RefSeq, Oct 2009]
  • Mouse(66898) BAI1-associated protein 2-like 1
  • Rat(304282) BAI1-associated protein 2-like 1
  • chicken(416437) BAI1-associated protein 2-like 1
  • dog(479748) BAI1-associated protein 2-like 1
  • cow(615412) BAI1-associated protein 2-like 1
  • domestic cat(101098023) BAI1-associated protein 2-like 1
  • naked mole-rat(101719088) BAI1-associated protein 2-like 1
  • domestic guinea pig(100724572) BAI1-associated protein 2-like 1
  • sheep(101114328) BAI1-associated protein 2-like 1

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Antibodies

Product Number
Description
Species Reactivity
Application
WH0055971M1
Monoclonal Anti-BAIAP2L1 antibody produced in mouse, clone 2A4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot