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Merck

ATP5A1

ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle

Synonyms:
ATP5A, ATP5AL2, ATPM, MC5DN4, MOM2, OMR, ORM, hATP1
Species:
UniProtKB ID:
Gene ID:
  • Human(498) Summary: This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the alpha subunit of the catalytic core. Alternatively spliced transcript variants encoding the different isoforms have been identified. Pseudogenes of this gene are located on chromosomes 9, 2, and 16. [provided by RefSeq, Mar 2012]
  • Mouse(11946) ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
  • Rat(65262) ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
  • Zebrafish(553755) ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
  • chicken(374159) ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
  • dog(480149) ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
  • Horse(100053178) ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
  • cow(282578) ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
  • domestic cat(101101674) ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
  • naked mole-rat(101705806) ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
  • domestic guinea pig(100729830) ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
  • Goat(100861332) ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
  • sheep(101111413) ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ATP5A1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-ATP5A1 (C-terminal) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-ATP5A1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-ATP5A1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot