Media composition plays a critical role in biopharmaceutical production as well as seed train expansion. The right combination of media, specifically designed for their purposes, in a seed train including a perfused N-1 step, can increase productivity in the final perfused production step. This indicates that specific companion media combinations can increase productivity gains with these intensified process formats. Using this technology combined with high cell density cryopreservation serves as an ideal possibility to intensify upstream processing.
In this webinar, you will learn:
- About intensified upstream processing
- How combining media, specifically designed for seed train, production, and harvest intensification, can increase the cell-specific productivity (Qp) in the final production stage
- How applying high cell density cryopreservation can significantly shorten your seed train
Speaker
Mona Bausch
Merck
Scientist, Cell Culture Media and Perfusion System R&D
Mona is a scientist in cell culture media and perfusion systems R&D. She received her B. Sc. and M. Sc. in biotechnology and biopharmaceutical technology at the University of Applied Sciences in Giessen. Before joining our company in 2015, she worked at Sanofi, Max Planck Institute of Biophysics, and Leica Microsystems. Mona has experience in downstream processing as well as quality management and quality control. She has worked on a variety of topics, including in-process reduction of ammonia, perfusion, and high cell density cryopreservation.
Pharma and biopharma manufacturing
- Cell Line Development
Duration:39min
Language:English
Session 1:presented January 16, 2020
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