Immunohistochemistry

Immunohistochemistry (IHC) is a biochemical method that uses antibodies that bind to specific antigens in a section of tissue. Similarly, immunocytochemistry (ICC) is suitable for identifying antigens in individual cell layers. IHC is commonly used to visualize proteins, carbohydrates, and lipids of interest in both healthy and diseased tissues, such as those found in cancerous tumors. Specific molecular markers are characteristic of cellular events such as proliferation or cell death (apoptosis). IHC is also widely used in basic research to understand the distribution and localization of biomarkers and differentially expressed proteins in different parts of biological tissue.