Duolink^® PLA – Protein Detection Technology

Inside every cell, there is a breakthrough waiting to be uncovered. The chance to change the origin of a human disease or discover the tell-tale sign of an irregular protein-protein interaction requires a powerful investigative tool and a streamlined approach. Rely on Duolink^® (proximity ligation assay) PLA to amplify your protein signals by 1000x and allow you to visually detect proteins and their interactions, all within a native cell. Our straightforward method provides:

• Visual protein interactions – both stable and transient
  
• Endogenous protein detection – no overexpression or genetic manipulation
  
• High specificity – use of two antibodies/probes eliminates false positives
  
• Single molecule sensitivity – rolling circle amplification makes proteins visible
  
• No special equipment needed – standard immunofluorescence methods
  
• Publication-ready results – compare image results from indirect methods (Co-Ip/WB)

Uncover the opportunities in your protein detection research with amplified performance and visual results.

How does Duolink^® PLA work?