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  • The distribution and function of phosphatidylserine in cellular membranes.

The distribution and function of phosphatidylserine in cellular membranes.

Annual review of biophysics (2010-03-03)
Peter A Leventis, Sergio Grinstein
ABSTRACT

Phosphatidylserine (PS) is the most abundant negatively charged phospholipid in eukaryotic membranes. PS directs the binding of proteins that bear C2 or gamma-carboxyglutamic domains and contributes to the electrostatic association of polycationic ligands with cellular membranes. Rather than being evenly distributed, PS is found preferentially in the inner leaflet of the plasma membrane and in endocytic membranes. The loss of PS asymmetry is an early indicator of apoptosis and serves as a signal to initiate blood clotting. This review discusses the determinants and functional implications of the subcellular distribution and membrane topology of PS.

MATERIALS
Product Number
Brand
Product Description

Avanti
TopFluor PS, Avanti Research - A Croda Brand 810283P, powder
Avanti
16:0-d31-18:1 PS, Avanti Research - A Croda Brand 860403P, powder
Avanti
16:0 PS-d62, Avanti Research - A Croda Brand 860401P, powder
Avanti
18:0 PS-d70, Avanti Research - A Croda Brand 860402P, powder
Avanti
16:0-d31-18:1 PS, Avanti Research - A Croda Brand 860403C
Avanti
16:0-06:0 NBD PS, Avanti Research - A Croda Brand 810192C
Avanti
18:1 Dansyl PS, Avanti Research - A Croda Brand
Avanti
18:1-06:0 NBD PS, Avanti Research - A Croda Brand
Avanti
18:1 NBD PS, Avanti Research - A Croda Brand 810198C
Avanti
16:0-06:0 NBD PS, Avanti Research - A Croda Brand 810192P, powder
Avanti
17:0 PS, Avanti Research - A Croda Brand
Avanti
4ME 16:0 PS, 1,2-diphytanoyl-sn-glycero-3-phospho-L-serine (sodium salt), chloroform
Avanti
18:0-18:2 PS, 1-stearoyl-2-linoleoyl-sn-glycero-3-phospho-L-serine (sodium salt), chloroform
Avanti
16:0-18:1 PS (POPS), Avanti Research - A Croda Brand
Avanti
18:0-18:2 PS, 1-stearoyl-2-linoleoyl-sn-glycero-3-phospho-L-serine (sodium salt), powder
Avanti
12:0 PS, 1,2-dilauroyl-sn-glycero-3-phospho-L-serine (sodium salt), powder
Avanti
16:0-20:4 PS, 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phospho-L-serine (sodium salt), chloroform
Avanti
18:0-22:6 PS, 1-stearoyl-2-docosahexaenoyl-sn-glycero-3-phospho-L-serine (sodium salt), chloroform
Avanti
14:0 PS, Avanti Research - A Croda Brand
Avanti
TopFluor PS, Avanti Research - A Croda Brand 810283C
Avanti
16:0-18:1 PS (POPS), Avanti Research - A Croda Brand
Avanti
4ME 16:0 PS, 1,2-diphytanoyl-sn-glycero-3-phospho-L-serine (sodium salt), powder
Avanti
18:1-12:0 NBD PS, Avanti Research - A Croda Brand 810195C
Avanti
18:0 PS, Avanti Research - A Croda Brand
Avanti
10:0 PS, 1,2-didecanoyl-sn-glycero-3-phospho-L-serine (sodium salt), powder
Avanti
06:0 PS, 1,2-dihexanoyl-sn-glycero-3-phospho-L-serine (sodium salt), chloroform
Avanti
22:6 PS, 1,2-didocosahexaenoyl-sn-glycero-3-phospho-L-serine (sodium salt), chloroform
Avanti
16:0 PS, Avanti Research - A Croda Brand
Avanti
16:0-18:2 PS, 1-palmitoyl-2-linoleoyl-sn-glycero-3-phospho-L-serine (sodium salt), chloroform
Avanti
06:0 PS, 1,2-dihexanoyl-sn-glycero-3-phospho-L-serine (sodium salt), powder