M2398

Metaproterenol hemisulfate salt

• Linear Formula: C₁₁H₁₇NO₃ · 1/2H₂SO₄
• CAS Number: 5874-97-5
• Molecular Weight: 260.30
• EC Number: 227-539-6
• MDL number: MFCD00058303
• UNSPSC Code: 12352107
• PubChem Substance ID: 24278539
• NACRES: NA.77

Properties

• Quality Level: 100
• originator: Boehringer Ingelheim
• SMILES string: OS(O)(=O)=O.CC(C)NCC(O)c1cc(O)cc(O)c1.CC(C)NCC(O)c2cc(O)cc(O)c2
• InChI: 1S/2C11H17NO3.H2O4S/c2*1-7(2)12-6-11(15)8-3-9(13)5-10(14)4-8;1-5(2,3)4/h2*3-5,7,11-15H,6H2,1-2H3;(H2,1,2,3,4)
• InChI key: MKFFGUZYVNDHIH-UHFFFAOYSA-N
• Gene Information: human ... ADRB2(154)

Description

Application

Metaproterenol hemisulfate salt has been used:

• as a β2-adrenoceptor agonist to study its effects on adenylyl cyclase stimulation in red blood cell deformability
• as an adrenergic agonist to study its effects on the stereoselective cell uptake by organic cation transporters in human embryonic kidney cell lines
• as a bronchodilator to study its effects on the activation of G-protein coupled receptors (GPCR)

Biochem/physiol Actions

Metaproterenol is a β2-adrenoceptor agonist. It shows bronchodilator activity and shows therapeutic effects against bronchitis, asthma, and emphysema.

Features and Benefits

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H332
• Precautionary Statements: P261 - P271 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Inhalation
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves