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L9625

Sigma-Aldrich

Leu-Gly

≥98% (TLC)

Synonym(s):

Leucylglycine

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About This Item

Empirical Formula (Hill Notation):
C8H16N2O3
CAS Number:
Molecular Weight:
188.22
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26

product name

Leu-Gly,

Assay

≥98% (TLC)

form

powder

color

white

storage temp.

−20°C

SMILES string

CC(C)C[C@H](N)C(=O)NCC(O)=O

InChI

1S/C8H16N2O3/c1-5(2)3-6(9)8(13)10-4-7(11)12/h5-6H,3-4,9H2,1-2H3,(H,10,13)(H,11,12)/t6-/m0/s1

InChI key

LESXFEZIFXFIQR-LURJTMIESA-N

Biochem/physiol Actions

Leucylglycine (Leu-Gly) is used to study the kinetics and speciation of copper(II)- cis, cis-1,3,5-triaminocyclohexane complex-promoted hydrolysis of dipeptides.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Cleavage of L-leucine-containing dipeptides by Clostridium butyricum.
Khelifa N, Brik M, Tessedre AC, et al.
Bioorganic & Medicinal Chemistry, 9, 109-112 (1999)
Irene L Gutiérrez et al.
Molecular neurobiology, 55(10), 7872-7885 (2018-02-27)
The decline in brain noradrenaline levels is associated with the progression of certain neurodegenerative diseases. This seems to be due, at least in part, to the ability of noradrenaline to limit glial activation and to reduce the damage associated with
Yuki Fujii et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 7(7-8), 843-851 (2002-08-31)
The hydrolysis of glycylglycine (GylGly), glycyl-L-leucine (GlyLeu), L-leucylglycine (LeuGly) and glycyl-DL-serine (GlySer) promoted by a copper(II)- cis, cis-1,3,5-triaminocyclohexane complex [Cu(II)TACH] was investigated at 70 degrees C and pH 7-10, using HPLC. The observed pseudo-first-order rate constants (k(obs)) and rate enhancing
Yu-Hsin Lin et al.
Nutrients, 10(10) (2018-10-03)
Hot water was used to obtain Chlorella sorokiniana hot water extract (HWE). Subsequently, this byproduct was freeze-dried, hydrolysed at 50 °C using Protease N to obtain C. sorokiniana protein hydrolysates (PN-1), and then digested with a gastrointestinal enzyme (PN-1G). The
Yu-Hsin Lin et al.
Nutrients, 11(6) (2019-06-19)
This research focuses on cobia skin hydrolysates and their antihypertensive effects via the inhibitory activities of angiotensin I-converting enzyme (ACE). Marine fish Cobia (Rachycentron canadum) skin was hydrolysed for 5 h using Protamex and Protease N to obtain the cobia

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