GPT
glutamic-pyruvate transaminase (alanine aminotransferase)
Synonyms:
AAT1, ALT1, GPT1
Species:
Human GPT (2875), Mouse Gpt (76282), Rat Gpt (81670), sheep GPT (101110488), sheep GPT (100286806), domestic guinea pig Gpt (100716607), naked mole-rat Gpt (101713635), fruit fly Gpt (5656924), Thale Cress GPT (818747), cow GPT (539188) ...More
UniProtKB ID:
Gene ID:
- Human(2875) Summary: This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.[provided by RefSeq, Nov 2009]
- Mouse(76282) glutamic pyruvic transaminase, soluble
- Rat(81670) glutamic-pyruvate transaminase (alanine aminotransferase)
- sheep(101110488) glutamic-pyruvate transaminase (alanine aminotransferase)
- sheep(100286806) glutamic-pyruvate transaminase (alanine aminotransferase)
- domestic guinea pig(100716607) glutamic-pyruvate transaminase (alanine aminotransferase)
- naked mole-rat(101713635) glutamic-pyruvate transaminase (alanine aminotransferase)
- fruit fly(5656924) Glutamate pyruvate transaminase
- Thale Cress(818747) UDP-GlcNAc:dolichol phosphate N-acetylglucosamine-1-phosphate transferase
- cow(539188) glutamic-pyruvate transaminase (alanine aminotransferase)
- domestic cat(101097207) glutamic-pyruvate transaminase (alanine aminotransferase)
- dog(609914) glutamic-pyruvate transaminase (alanine aminotransferase)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-GPT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab1,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-GPT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab2,
Species Reactivity
human
Application
immunohistochemistry
ANTI-GPT antibody produced in mouse, clone M1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Monoclonal Anti-GPT antibody produced in mouse, clone 1F10, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-GPT (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, guinea pig, human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Kits
Product Number
Description
Species
ALT Activity Assay, sufficient for 100 colorimetric or fluorometric tests,
Species
human, mouse, rat