化驗
≥98% (HPLC)
形狀
solid
溶解度
DMSO: 16 mg/mL
儲存溫度
2-8°C
SMILES 字串
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC=NC2=O
InChI
1S/C9H12N2O5/c12-4-5-6(13)7(14)8(16-5)11-3-1-2-10-9(11)15/h1-3,5-8,12-14H,4H2/t5-,6-,7-,8-/m1/s1
InChI 密鑰
RPQZTTQVRYEKCR-WCTZXXKLSA-N
生化/生理作用
Zebularine 是一种胞苷类似物,胞苷脱氨酶抑制剂和 DNA 去甲基化剂。
特點和優勢
该化合物是基因调控研究的特色产品。点击此处,发现更多特色基因调控产品。如需了解有关生物活性小分子在其他研究领域的更多信息,请访问sigma.com/ discover-bsm。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
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The maintenance of genome integrity over cell divisions is critical for plant development and the correct transmission of genetic information to the progeny. A key factor involved in this process is the STRUCTURAL MAINTENANCE OF CHROMOSOME5 (SMC5) and SMC6 (SMC5/6)
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Sepsis is among the leading causes of death with no specific etiology or treatment. Increase in health burden in terms of cost, morbidity, and mortality is the reason behind the continuous search for different treatment modalities which involve several targets/approach
Endocrinology, 158(6), 1838-1848 (2017-04-12)
Many of the best-studied neural sex differences relate to differences in cell number and are due to the hormonal control of developmental cell death. However, several prominent neural sex differences persist even if cell death is eliminated. We hypothesized that
Bioscience, biotechnology, and biochemistry, 82(7), 1159-1164 (2018-04-25)
Malignant mesothelioma is an asbestos-related aggressive tumor and current therapy remains ineffective. Zebularine as a DNA methyltransferase (DNMT) inhibitor has an anti-tumor effect in several human cancer cells. The aim of the present study was to investigate whether zebularine could
Frontiers in genetics, 9, 254-254 (2018-08-02)
Large-scale tumor genome sequencing projects have revealed a complex landscape of genomic mutations in multiple cancer types. A major goal of these projects is to characterize somatic mutations and discover cancer drivers, thereby providing important clues to uncover diagnostic or
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