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Key Documents

SAB5200102

Sigma-Aldrich

Anti-SLC9A3 antibody produced in rabbit

1 mg/mL, affinity isolated antibody

别名:

Anti-NHE3, Anti-Slc9a3

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous glycerol solution

分子量

antigen predicted mol wt 84 kDa

物種活性

rat, mouse

濃度

1 mg/mL

技術

immunocytochemistry: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

一般說明

Solute carrier family 9 member A3 (SLC9A3) is also known as Na+/H+ exchanger 3 (NHE3) and is expressed in the brush border epithelium. The gene ID of the protein is 24784.

特異性

Detects ~84 kDa.

免疫原

AA809 to 831 of rat sequence

生化/生理作用

Solute carrier family 9 member A3 (SLC9A3) is an exchanger which takes part in the reabsorption of water and sodium chloride in the proximal tubule of kidneys. It exchanges one Na+ (from the lumen) with one H+ (from the cytosol).

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

PBS, 50% glycerol, and 0.09% sodium azide

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Srinivas Rengarajan et al.
American journal of physiology. Renal physiology, 306(9), F1059-F1068 (2014-03-07)
Dietary potassium loading results in rapid kaliuresis, natriuresis, and diuresis associated with reduced phosphorylation (p) of the distal tubule Na(+)-Cl(-) cotransporter (NCC). Decreased NCC-p inhibits NCC-mediated Na(+) reabsorption and shifts Na(+) downstream for reabsorption by epithelial Na(+) channels (ENaC), which
Jens Christian Brasen et al.
American journal of physiology. Renal physiology, 307(11), F1249-F1262 (2014-10-10)
The proximal tubule Na(+)/H(+) exchanger 3 (NHE3), located in the apical dense microvilli (brush border), plays a major role in the reabsorption of NaCl and water in the renal proximal tubule. In response to a rise in blood pressure NHE3

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