生物源
rabbit
品質等級
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
mouse, human
濃度
1.3 mg/mL
技術
immunohistochemistry: 1:25- 1:100
同型
IgG
登錄號
NP_001073922.2
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... INTS1(26173)
特異性
The antibody detects endogenous levels of total INTS1 protein.
免疫原
Synthetic peptide corresponding to residues near the N terminal of human integrator complex subunit 1
應用
Anti-INTS1 antibody produced in rabbit is suitable for immunohistochemistry studies at a dilution of 1:25 - 1:100.
生化／生理作用
INTS1 (Integrator complex subunit 1), a large nuclear protein, involved in the processing of small nuclear RNA as a major component of the Integrator complex. During transcriptional regulation and in RNA processing, it directly binds to the C-terminal domain of the RNA polymerase II largest subunit. It has been reported that INTS1 is also involved in different cell support processes such as the formation of a scaffold for the assembly of integrator complex.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
David Baillat et al.
Cell, 123(2), 265-276 (2005-10-22)
The C-terminal domain (CTD) of RNA polymerase II (RNAPII) is an essential component of transcriptional regulation and RNA processing of protein-coding genes. A large body of data also implicates the CTD in the transcription and processing of RNAPII-mediated small nuclear
Toshiyuki Hata et al.
Biochimica et biophysica acta, 1773(7), 1039-1051 (2007-06-05)
The KIAA1440 protein contains no significant domains that allow for a prediction of its function, despite the fact that it is an extremely large protein comprising 2222 amino acids. In our current study, we show that the developing KIAA1440(-/-) mouse
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