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物種活性
human, mouse, rat
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
enzyme immunoassay: suitable
輸入
sample type serum
sample type culture supernatant(s)
sample type plasma
sample type cell lysate
assay range
inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 1.66 pg/mL
standard curve range: 0.1–1000 pg/mL
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... NPPB(4879)
一般說明
BNP 酶免疫分析 (EIA) 试剂盒是基于竞争酶免疫分析原理的体外定量检测 BNP 肽的方法。
免疫原
脑钠肽，合成肽
應用
仅用于研究目的。不用于诊断程序。
脑钠肽 EIA 试剂盒已用于测定人新生儿心室心肌细胞培养分泌的脑钠肽 (BNP)。
脑钠肽 EIA 试剂盒已用于测定人新生儿心室心肌细胞培养分泌的脑钠肽 (BNP)。
生化／生理作用
哺乳动物脑利钠肽 (BNP) 和心房利钠肽 (ANP) 具有调节血压和心脏重构等多种生理功能。BNP 可作为有症状的左心室 (LV) 功能障碍患者左心室舒张末压升高的潜在生物标志物。在急性心肌梗死 (AMI) 患者中观察到 BNP 表达升高。BNP 还涉及多种生物学功能，如利尿、利钠、降压和抑制醛固酮分泌。
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Plasma brain natriuretic peptide as a biochemical marker of high left ventricular end-diastolic pressure in patients with symptomatic left ventricular dysfunction.
Maeda K
American Heart Journal, 135(5 pt 1), 825-832 (1998)
Azar Hosseini et al.
Frontiers in pharmacology, 13, 909079-909079 (2022-06-28)
Background: Doxorubicin as an anti-cancer drug causes cardiotoxicity, limiting its tolerability and use. The mechanism of toxicity is due to free radical production and cardiomyocytes injury. This research evaluated Rheum turkestanicum (R.turkestanicum) extract against doxorubicin cardiotoxicity due to its considerable
Induction of HO-1 by carbon monoxide releasing molecule-2 attenuates thrombin-induced COX-2 expression and hypertrophy in primary human cardiomyocytes.
Chien PT
Toxicology and Applied Pharmacology, 289(2), 349-359 (2015)
A new natriuretic peptide in porcine brain.
Sudoh T
Nature, 332(6159), 78-81 (1988)
Jiakan Weng et al.
Journal of cellular and molecular medicine, 23(2), 1050-1058 (2018-11-20)
Obesity is associated with increased cardiovascular morbidity and mortality, but the direct signals to initiate or exaggerate cardiomyopathy remain largely unknown. Present study aims to explore the pathophysiological role of autotaxin/lysophosphatidic acid (LPA) in the process of cardiomyopathy during obesity.
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