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Merck
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Key Documents

PLA0078

Sigma-Aldrich

Rabbit anti-KAP-1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

别名:

E3 SUMO-protein ligase TRIM28, KAP-1, KAP1, KRAB [Kruppel-associated box domain]-associated protein 1, KRAB-associated protein 1, KRAB-interacting protein 1, KRIP-1, PPP1R157, RING finger protein 96, RNF96, TF1B, TIF1-beta, TIF1B, Tripartite motif-containing protein 28, nuclear corepressor KAP-1, protein phosphatase 1, regulatory subunit 157, transcriptional intermediary factor 1-beta

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity purified immunoglobulin

抗體產品種類

primary antibodies

等級

Powered by Bethyl Laboratories, Inc.

物種活性

mouse, human

濃度

1 mg/mL

技術

immunocytochemistry: 1:500-1:2,500
immunohistochemistry: 1:500-1:2,000
immunoprecipitation (IP): 2-10 μg/mg
western blot: 1:2,000-1:10,000

登錄號

NP_005753.1

運輸包裝

wet ice

儲存溫度

2-8°C

基因資訊

rabbit ... KAP-1(10155)

免疫原

The epitope recognized by PLA0078 maps to a region between residue 1 and 50 of human Tripartite Motif-Containing 28 using the numbering given in entry NP_005753.1 (GeneID 10155).

外觀

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

其他說明

KAP-1 (KRAB-Associated Protein 1) is a member of the tripartite motif RBCC/Trim domain family that contains a RING finger domain, B boxes, and an alpha helical coiled coil region. KAP-1 functions as a corepressor by interacting with the KRAB domain of KRAB zinc-finger transcriptional repressors. KAP-1 also appears to function as a scaffold for chromatin-remodeling complexes involved in transcriptional repression.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Estela Cruvinel et al.
Human molecular genetics, 23(17), 4674-4685 (2014-04-25)
Prader-Willi syndrome (PWS), a disorder of genomic imprinting, is characterized by neonatal hypotonia, hypogonadism, small hands and feet, hyperphagia and obesity in adulthood. PWS results from the loss of paternal copies of the cluster of SNORD116 C/D box snoRNAs and

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