化驗
≥98% (HPLC and titration)
形狀
powder
顏色
white
mp
175-177 °C (lit.)
溶解度
H2O: 1 g/mL
ethanol: soluble
SMILES 字串
[Br-].CN(C)C(=O)Oc1cccc(c1)[N+](C)(C)C
InChI
1S/C12H19N2O2.BrH/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5;/h6-9H,1-5H3;1H/q+1;/p-1
InChI 密鑰
LULNWZDBKTWDGK-UHFFFAOYSA-M
基因資訊
human ... ACHE(43)
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應用
溴新斯的明已被用作乙酰胆碱酯酶（AChE）抑制剂:
- 用于控制乙酰胆碱酯酶在史氏菊海鞘（Botryllus schlosseri）冠状器官的反应特异性。
- 用于研究其对幽门环形平滑肌条（PCSMS）异常收缩的影响。
- 用于研究其对袋细胞神经元去极化的影响 。
生化／生理作用
溴新斯的明是一种季胺。 它通过抑制胆碱酯酶活性而参与延长并增强乙酰胆碱的毒蕈碱和烟碱作用。它在麻醉作用中用于逆转竞争性神经肌肉阻滞剂产生的神经肌肉阻滞。
类似于毒扁豆碱的乙酰胆碱酯酶的可逆抑制剂，但是不能穿过血脑屏障。
特點和優勢
该化合物收录于受体分类和信号转导手册的《乙酰胆碱合成与代谢》页面。想要浏览手册的其他页面， 请单击此处。
訊號詞
Danger
危險分類
Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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