用途
sufficient for 100 colorimetric tests
檢測方法
colorimetric
相關疾病
cardiovascular diseases; cancer; hematological disorder
儲存溫度
−20°C
一般說明
醛脱氢酶（ALDH）是一类催化外源性醛和内源性醛的代谢、防止潜在反应性醛和毒性醛及其代谢物的积累的酶。除了它们在醛代谢中的作用外，ALDH酶还在其他细胞过程中起关键作用，例如细胞增殖，分化和存活。ALDH家族成员的突变与许多疾病有关，如心脏病、白内障和某些癌症。ALDH活性也可以作为某些干细胞群（包括造血干细胞和某些癌症干细胞）的标志物。
應用
醛脱氢酶活性比色检测试剂盒用于检测醛脱氢酶的活性。
特點和優勢
与高通量处理系统相容。
適合性
适用于对包括组织和细胞在内的多种样品中的醛脱氢酶（ALDH）进行测定
原則
醛脱氢酶活性比色检测试剂盒提供了一种可简单直接地检测各种样品中NAD依赖性ALDH活性的方法。ALDH活性通过酶偶联法检测，其中乙醛被ALDH氧化生成NADH，NADH与探针反应，产生比色(450 nm)产物，该产物与存在的ALDH活性成比例。一单位ALDH是指该酶在室温、pH 8.0条件下每分钟产生1.0 μmM NADH的量。
訊號詞
Danger
危險聲明
危險分類
Carc. 1B - Eye Dam. 1 - Skin Corr. 1B
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
其他客户在看
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Cancer stem cells (CSCs) are considered the roots of cancer metastasis and recurrence (CSCs), due in part to their self-renewal and therapy resistance properties. However, the underlying mechanisms for the regulation of CSC stemness are poorly understood. Recently, increasing evidence
商品
AldeRed™ 588-A is a red fluorescent live cell probe that detects ALDH activity used to identify cancer stem cells and progenitor cells in culture. Cancer stem cells (CSCs) are subpopulations of cancer cells that can self-renew, generate diverse cells in the tumor mass, and sustain tumorigenesis. Some researchers believe that cancer arises from cancer stem cells that originate as a result of mutational hits on normal stem cells.
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