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生物源
Salmonella enterica (Serotype enteritidis)
品質等級
形狀
lyophilized powder
純化經由
phenol extraction
雜質
<3% Protein (Lowry)
顏色
white to faint yellow
溶解度
water: 0.90-1.10 mg/mL, slightly hazy to turbid, colorless to faintly yellow
運輸包裝
ambient
儲存溫度
2-8°C
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一般說明
本品为肠炎沙门菌中提取的苯酚。来源菌株为 ATCC 13076。肠炎沙门氏菌的脂多糖在小鼠脾细胞中具有致突变性,并在这些细胞中引起空斑形成反应。
應用
脂多糖 (LPS) 是革兰氏阴性菌细胞壁的特征性成分。LPS 及其脂质 A 部分通过 Toll 样受体 4 (TLR4) 刺激天然免疫系统的细胞。
生化/生理作用
脂多糖(LPS)位于膜的外层,并且在非包封的菌株中,其暴露于细胞表面。它们有助于外膜的完整性,并可保护细胞免受胆汁盐和亲脂性抗生素的作用。
準備報告
该产品可溶于水(5mg / ml)或细胞培养基(1mg / ml),产生浑浊的淡黄色溶液。当涡旋并升温至70-80 oC后,在盐水中可获得更高浓度的溶液(20mg/ml),但仍然是浑浊的溶液。脂多糖是一种在各种溶剂中都形成胶束的分子。在水和磷酸盐缓冲盐水中可观察到浑浊的溶液。有机溶剂无法使溶液变澄清。甲醇会产生含有漂浮物的混浊悬浮液,而水会产生均匀的混浊溶液。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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