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Merck

GW20079F

Sigma-Aldrich

Anti-Vitamin D-Binding Protein antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

别名:

Anti-VDBP

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

chicken

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

human

技術

indirect ELISA: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... GC(2638)

免疫原

Immunogen Sequence: GI # 32483410, sequence 1-474
Vitamin D-binding protein (native protein).

應用

Anti-Vitamin D-Binding Protein antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

Vitamin D-binding protein (also known as gc-globulin) is a protein encoded by the GC gene in humans. It transports vitamin D metabolites in the circulation. Both vitamin D metabolites and vitamin D binding proteins (VDBP) are associated with asthma (regulation in the lung during acute allergen-induced airway inflammation). Vitamin D-binding protein (VDBP) haplotypes also influence free vitamin D levels.

外觀

Solution in phosphate buffered saline containing 0.02% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Aledie Navas-Nazario et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 112(6), 519-524 (2014-04-22)
Potential vitamin D-related influences on inflammatory diseases such as asthma are controversial, including the suggestion that vitamin D insufficiency is associated with increased asthma morbidity. Vitamin D-binding protein transports vitamin D metabolites in the circulation. Single nucleotide polymorphisms in the
A G Randolph et al.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 44(2), 231-237 (2014-01-23)
Between 75 000 and 125 000 U.S. infants are hospitalized for respiratory syncytial virus (RSV) bronchiolitis every year. Up to half will be diagnosed with asthma in later childhood. Vitamin D deficiency has been associated with susceptibility to asthma and respiratory infections.
K Bratke et al.
Clinical and experimental immunology, 177(1), 366-372 (2014-04-16)
Allergic asthma is a chronic disease of the airways associated with airway hyperresponsiveness, a variable degree of airflow obstruction, airway remodelling and a characteristic airway inflammation. Factors of the vitamin D axis, which include vitamin D metabolites and vitamin D

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