跳转至内容
Merck
所有图片(1)

文件

A4188

Sigma-Aldrich

N-Acetyl-Ile-Glu-Thr-Asp-7-Amido-4-methylcoumarin

≥97% (HPLC), powder

别名:

Ac-IETD-AMC

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C31H41N5O12
分子量:
675.68
MDL號碼:
MFCD01630896
分類程式碼代碼:
12352209
PubChem物質ID:
24890834
NACRES:
NA.32

化驗

≥97% (HPLC)

形狀

powder

顏色

white

溶解度

DMSO/DMF: 1 mg/mL

儲存溫度

−20°C

SMILES 字串

CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc2C(C)=CC(=O)Oc2c1

InChI

1S/C31H41N5O12/c1-6-14(2)26(32-17(5)38)30(46)34-20(9-10-23(39)40)28(44)36-27(16(4)37)31(47)35-21(13-24(41)42)29(45)33-18-7-8-19-15(3)11-25(43)48-22(19)12-18/h7-8,11-12,14,16,20-21,26-27,37H,6,9-10,13H2,1-5H3,(H,32,38)(H,33,45)(H,34,46)(H,35,47)(H,36,44)(H,39,40)(H,41,42)/t14-,16+,20-,21-,26-,27-/m0/s1

InChI 密鑰

ZYTCBVQZQSFKHQ-HGZCCCDHSA-N

基因資訊

human ... CARD8(22900) , CASP8(841) , CASP8AP2(9994) , CFLAR(8837) , GZMB(3002)
mouse ... CFLAR(117279) , GZMB(171528)
rat ... CASP8(12370) , CFLAR(12633) , GZMB(14939) , RGD1561819(502004) , RGD1562700(502007)

Amino Acid Sequence

NAc-Ile-Glu-Thr-Asp-AMC

應用

Fluorogenic substrate for caspase 8 and granzyme B.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

其他客户在看

Slide 1 of 1

1 of 1

7-氨基放线菌素D ~97% (HPLC), powder

Sigma-Aldrich

A9400

7-氨基放线菌素D

N A Thornberry et al.
The Journal of biological chemistry, 272(29), 17907-17911 (1997-07-18)
There is compelling evidence that members of the caspase (interleukin-1beta converting enzyme/CED-3) family of cysteine proteases and the cytotoxic lymphocyte-derived serine protease granzyme B play essential roles in mammalian apoptosis. Here we use a novel method employing a positional scanning
Fabien J Cousin et al.
PloS one, 7(3), e31892-e31892 (2012-03-24)
Gastric cancer is one of the most common cancers in the world. The "economically developed countries" life style, including diet, constitutes a risk factor favoring this cancer. Diet modulation may lower digestive cancer incidence. Among promising food components, dairy propionibacteria
Huili Zhu et al.
Scientific reports, 6, 26859-26859 (2016-06-01)
Glucagon-like peptide-1 (GLP-1) is an incretin hormone that increases glucose-dependent insulin secretion to reduce the glucose level. Liraglutide, a long-acting GLP-1 analogue, has been found to have neuroprotective action in various experimental models. However, the protective mechanisms of liraglutide in
Bernardo Nuche-Berenguer et al.
American journal of physiology. Gastrointestinal and liver physiology, 310(11), G1015-G1027 (2016-04-02)
In pancreatic acinar cells, the Src family of kinases (SFK) is involved in the activation of several signaling cascades that are implicated in mediating cellular processes (growth, cytoskeletal changes, apoptosis). However, the role of SFKs in various physiological responses such
Fabien J Cousin et al.
Oncotarget, 7(6), 7161-7178 (2016-01-16)
TNF-Related Apoptosis-Inducing Ligand (TRAIL) is a well-known apoptosis inducer, which activates the extrinsic death pathway. TRAIL is pro-apoptotic on colon cancer cells, while not cytotoxic towards normal healthy cells. However, its clinical use is limited by cell resistance to cell
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门