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Merck

44001

Sigma-Aldrich

N-Acetyl-D-glucosamin-6-sulfat 钠盐

≥98.0% (TLC)

别名:

GlcNAc-6S

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About This Item

线性分子式:
C8H14NO9SNa
分子量:
323.25
MDL號碼:
分類程式碼代碼:
12352201
PubChem物質ID:
NACRES:
NA.25

生物源

synthetic

描述

Mixed anomers

化驗

≥98.0% (TLC)

形狀

solid

光學活性

[α]20/D 32.0±2.0, c = 0.1% (w/v) in water

技術

thin layer chromatography (TLC): suitable

顏色

colorless

儲存溫度

−20°C

SMILES 字串

[Na+].CC(=O)N[C@H]1C(O)O[C@H](COS([O-])(=O)=O)[C@@H](O)[C@@H]1O

InChI

1S/C8H15NO9S.Na/c1-3(10)9-5-7(12)6(11)4(18-8(5)13)2-17-19(14,15)16;/h4-8,11-13H,2H2,1H3,(H,9,10)(H,14,15,16);/q;+1/p-1/t4-,5-,6-,7-,8?;/m1./s1

InChI 密鑰

CBUJZKTVEFVBBG-FROKLYQUSA-M

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應用

N-Acetyl-D-glucosamine 6-sulfate (GlcNAc-6S) is used as a substrate and inhibitor to identify, differentiate and characterize various sulfatase(s), especially N-acetylglucosamine-6-sulphatase(s).

包裝

Bottomless glass bottle. Contents are inside inserted fused cone.

其他說明

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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N H Elçioglu et al.
Genetic counseling (Geneva, Switzerland), 20(2), 133-139 (2009-08-05)
A novel loss-of-function mutation in the GNS gene causes Sanfilippo syndrome type D: Mucopolysaccharidosis type IIID (MIM 252940) is the least common form of the four subtypes of Sanfilippo syndrome. It is an autosomal recessive lysosomal disorder caused by a
Shengyuan Xu et al.
The Biochemical journal, 387(Pt 3), 841-847 (2004-12-15)
A 75 kDa protein was purified to homogeneity from granule extracts of normal human granulocytes using Sephadex G-75 chromatography, Mono-S cation exchange chromatography and chromatofocusing. The protein consisted of one chain with a molecular mass of 75 kDa, as determined
Andrew J Nok et al.
Journal of biochemical and molecular toxicology, 17(1), 59-66 (2003-03-05)
The venom of Naja nigricolis was found to contain a high level of the enzyme aryl sulfatase. The enzyme was isolated from the venom of N. nigriclois and purified to electrophoretic homogeneity by gel chromatography on Sephadex G-100, DEAE-cellulose, and
Andrea Mok et al.
Genomics, 81(1), 1-5 (2003-02-08)
Mucopolysaccharidosis type IIID (MPS IIID; Sanfilippo syndrome type D; MIM 252940) is caused by deficiency of the activity of N-acetylglucosamine-6-sulfatase (GNS), which is normally required for degradation of heparan sulfate. The clinical features of MPS IIID include progressive neurodegeneration, with

商品

Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.

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