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Merck

18726

Sigma-Aldrich

Nα-Methyl-L-ornithine monohydrochloride

≥98% (TLC), powder

别名:

(S)-5-Amino-2-(methylamino)pentanoic acid hydrochloride, N-Me-Orn-OH · HCl

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About This Item

经验公式(希尔记法):
C6H14N2O2 · HCl
CAS号:
分子量:
182.65
Beilstein:
6117952
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:
NACRES:
NA.32

product name

Nα-Methyl-L-ornithine monohydrochloride, ≥98% (TLC)

品質等級

化驗

≥98% (TLC)

形狀

powder

光學活性

[α]/D +27.0±1.0°, c = 1 in 1 M HCl

成份

carbon, 38.7-40.2%
nitrogen, 14.9-15.7%

SMILES 字串

Cl.CN[C@@H](CCCN)C(O)=O

InChI

1S/C6H14N2O2.ClH/c1-8-5(6(9)10)3-2-4-7;/h5,8H,2-4,7H2,1H3,(H,9,10);1H/t5-;/m0./s1

InChI 密鑰

OUPNMQRLBAANLP-JEDNCBNOSA-N

生化/生理作用

Nα-Methyl-L-ornithine has been identified as an inhibitor of nitric oxidase synthase in macrophages.

包裝

Bottomless glass bottle. Contents are inside inserted fused cone.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

防範說明

危險分類

Eye Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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T B McCall et al.
British journal of pharmacology, 102(1), 234-238 (1991-01-01)
1. The synthesis of nitric oxide (NO) from L-arginine by rat peritoneal neutrophils (PMN) and the murine macrophage cell-line J774 and the inhibition of this synthesis by N-iminoethyl-L-ornithine (L-NIO), NG-monomethyl-L-arginine (L-NMMA), NG-nitro-L-arginine (L-NNA) and its methyl ester (L-NAME) were investigated.
D J Gordon et al.
Biochemistry, 40(28), 8237-8245 (2001-07-11)
A potential goal in the prevention or therapy of Alzheimer's disease is to decrease or eliminate neuritic plaques composed of fibrillar beta-amyloid (Abeta). In this paper we describe N-methyl amino acid containing congeners of the hydrophobic "core domain" of Abeta

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