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Key Documents

SCT094

Sigma-Aldrich

BioTracker NIR FolateReceptor Live Cell Dye

别名:

BioTracker NIR FolateReceptor Live Cell Dye

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About This Item

分類程式碼代碼:
12352207
NACRES:
NA.47

形狀

lyophilized

分子量

calculated mol wt 1196.30

包裝

pkg of 1 mg

製造商/商標名

Millipore

儲存條件

protect from light

增長模式

N/A

運輸包裝

ambient

儲存溫度

−20°C

一般說明

Folate receptors (FRs) are membrane bound surface proteins involved in folic acid uptake. FRs are frequently overexpressed in a large number of solid tumors including cancers of the ovary, breast and lung. FRs are attractive candidates for cancer imaging and targeted therapies.BioTracker NIR Folate Receptor Live Cell Dye is a near-infrared (NIR) fluorescent probe for the detection of folate receptors in vivo. This probe exhibits very low background fluorescence and high tumor-to-background ratio in FR-expressing tumor-bearing mice within 30 min (1).Reference:1. Numasawa, Koji, et al. "A Fluorescent Probe for Rapid, High‐Contrast Visualization of Folate‐Receptor‐Expressing Tumors In Vivo." Angewandte Chemie International Edition 59.15 (2020): 6015-6020.

應用

Purity ≥ 95% confirmed by HPLC. Identification confirmed by HNMR, LC-MS, and elemental analysis.

特點和優勢

Near-Infrared probe for detection and visualization of folate receptors in vivo.

外觀

Lyophilized. Green solid.

儲存和穩定性

Store at -20°C, desiccate and protect from light.
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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