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生物源
human
品質等級
重組細胞
expressed in Sf21 cells
分子量
Mw 48.7 kDa
製造商/商標名
Upstate®
技術
activity assay: suitable (kinase)
NCBI登錄號
UniProt登錄號
基因資訊
human ... RPS6KB1(6198)
一般說明
N-terminal His6-tagged, recombinant amino acids 1-421 of human p70 S6 kinase
Product Source: Expressed in Sf21 cells
生化/生理作用
Protein Target: p70S6K
Target Sub-Family: AGC
包裝
Also available in 250μg size as catalog # 14-486M.
品質
Routinely evaluated by phosphorylation of S6 Kinase/Rsk-2 Substrate Peptide 2
外觀
Ni2+/NTA-agarose
儲存和穩定性
6 months at -70°C
其他說明
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
The Journal of biological chemistry, 278(30), 28130-28138 (2003-05-13)
We report here for the first time the detection of the ribosomal p70S6 kinase (p70S6K) in a hematopoietic cell, the neutrophil, and the stimulation of its enzymatic activity by granulocyte macrophage colony-stimulating factor (GM-CSF). GM-CSF modified the Vmax of the
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