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Merck

860637P

Avanti

Galactosyl(β) Sphingosine-d5

Avanti Research - A Croda Brand 860637P, powder

别名:

D-galactosyl-β1-1′-D-erythro-sphingosine-d5

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About This Item

经验公式(希尔记法):
C24H42D5NO7
分子量:
466.66
分類程式碼代碼:
12352211
NACRES:
NA.12

形狀

powder

包裝

pkg of 1 × 1 mg (860637P-1mg)

製造商/商標名

Avanti Research - A Croda Brand 860637P

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@](/C=C/CCCCCCCCCCCC([2H])(C([2H])([2H])[2H])[2H])(O)[C@](N)([H])CO[C@H](O1)[C@H](O)[C@@H](O)[C@H]([C@H]1CO)O

應用

Galactosyl(β) Sphingosine-d5 has been used as an internal standard for the quantification of galactosylsphingosine, in the extracts from the mouse cerebellum by liquid chromatography-tandem mass spectrometry.

生化/生理作用

Galactosylsphingosine, also known as psychosine, has an ability to induce apoptosis in various types of cells including oligodendrocytes. It is a toxic metabolite. Accumulation of this cytotoxic sphingolipid in the brain due to the deficiency of galactocerebrosidase (GALC) leads to the development of Krabbe disease.

包裝

5 mL Amber Glass Screw Cap Vial (860637P-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

閃點(°F)

No data available

閃點(°C)

No data available


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Victoria Schiffer et al.
PloS one, 15(1), e0227077-e0227077 (2020-01-14)
Gaucher disease is caused by a deficiency in glucocerebrosidase that can result in non-neuronal as well as neuronal symptoms. Common visceral symptoms are an increased organ size, specifically of the spleen, and glucosylceramide as well as glucosylsphingosine substrate accumulations as

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