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Merck

804347

Sigma-Aldrich

3-nitro-N-[(3S)-tetrahydro-2-oxo-furanyl]-Benzeneacetamide

别名:

LasR inhibitor, LuxR activator

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About This Item

经验公式(希尔记法):
C12H12N2O5
分子量:
264.23
分類程式碼代碼:
12352200
NACRES:
NA.22

形狀

solid

儲存溫度

−20°C

應用

PHL has varied activity depending on species, for example serving as either a strong LuxR-type receptor activator (e.g.: of LuxR in V. fischeri and of ExpR1 and ExpR2 in Pectobacterium carotovora) or a strong inhibitor (e.g.: of LasR in P. aeruginosa)

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Andrew G Palmer et al.
Chembiochem : a European journal of chemical biology, 12(1), 138-147 (2010-12-15)
Many bacteria use quorum sensing (QS) to regulate cell-density dependent phenotypes that play critical roles in the maintenance of their associations with eukaryotic hosts. In Gram-negative bacteria, QS is primarily controlled by N-acylated L-homoserine lactone (AHL) signals and their cognate
Grant D Geske et al.
Journal of the American Chemical Society, 129(44), 13613-13625 (2007-10-12)
Bacteria use a language of low molecular weight ligands to assess their population densities in a process called quorum sensing. This chemical signaling process plays a pivotal role both in the pathogenesis of infectious disease and in beneficial symbioses. There

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Quorum sensing is a chemical communication mechanism used by many common bacteria to initiate group behaviors. It plays an important role in the establishment of infection by pathogens and in mediating certain symbioses.

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