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Merck

467936

Sigma-Aldrich

3,4,5-三氯吡啶

98%

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About This Item

经验公式(希尔记法):
C5H2Cl3N
CAS号:
分子量:
182.44
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

98%

mp

75-77 °C (dec.) (lit.)

SMILES 字串

Clc1cncc(Cl)c1Cl

InChI

1S/C5H2Cl3N/c6-3-1-9-2-4(7)5(3)8/h1-2H

InChI 密鑰

KKWRVUBDCJQHBZ-UHFFFAOYSA-N

一般說明

3,4,5-Trichloropyridine is a pyridine derivative. It undergoes oxidation with trifluoroacetic anhydride (TFAA) in the presence of hydrogen peroxide urea complex.

應用

3,4,5-Trichloropyridine may be employed as a secondary standard in quantitative NMR (qNMR) studies.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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A practical, efficient, and rapid method for the oxidation of electron deficient pyridines using trifluoroacetic anhydride and hydrogen peroxide-urea complex.
Caron S, et al.
Tetrahedron Letters, 41(14), 2299-2302 (2000)
Torgny Rundlöf et al.
Journal of pharmaceutical and biomedical analysis, 52(5), 645-651 (2010-03-09)
In quantitative NMR (qNMR) selection of an appropriate internal standard proves to be crucial. In this study, 25 candidate compounds considered to be potent internal standards were investigated with respect to the ability of providing unique signal chemical shifts, purity
Torgny Rundlöf et al.
Journal of pharmaceutical and biomedical analysis, 93, 111-117 (2013-11-12)
Standards are required in quantitative NMR (qNMR) to obtain accurate and precise results. In this study acetanilide was established and used as a primary standard. Six other chemicals were selected as secondary standards: 3,4,5-trichloropyridine, dimethylterephthalate, maleic acid, 3-sulfolene, 1,4-bis(trimethylsilyl)benzene, and
Shi Shen et al.
Journal of pharmaceutical and biomedical analysis, 114, 190-199 (2015-06-13)
This study investigated the accuracy of the quantitative NMR method for purity determination of ACE inhibitors reference standards and the discovery of two pairs of new diastereoisomers. Six types of ACE inhibitors, imidapril hydrochloride, benazepril hydrochloride, lisinopril, enalapril maleate, quinapril
Monika Johansson et al.
Journal of pharmaceutical and biomedical analysis, 100, 215-229 (2014-08-30)
An effective screening procedure to identify and quantify active pharmaceutical substances in suspected illegal medicinal products is described. The analytical platform, consisting of accurate mass determination with liquid chromatography time-of-flight mass spectrometry (LC-QTOF-MS) in combination with nuclear magnetic resonance (NMR)

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