跳转至内容
Merck

RUNX2

runt-related transcription factor 2

别名:
AML3, CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, PEA2aA, PEBP2aA
物种:
UniProtKB ID:
基因ID:
  • Human(860) Summary: This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2008]
  • Mouse(12393) runt related transcription factor 2
  • Rat(367218) runt-related transcription factor 2
  • domestic guinea pig(100734175) runt-related transcription factor 2
  • naked mole-rat(101724767) runt-related transcription factor 2
  • Domestic Rabbit(100008943) runt-related transcription factor 2
  • cow(536911) runt-related transcription factor 2
  • sheep(101115489) runt-related transcription factor 2
  • Goat(100861217) runt-related transcription factor 2
  • chicken(373919) runt-related transcription factor 2
  • dog(449531) runt-related transcription factor 2
  • Horse(100033890) runt-related transcription factor 2
  • domestic cat(101089612) runt-related transcription factor 2
  • dog(474923) runt-related transcription factor 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
抗-RUNX2 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-RUNX2 antibody produced in mouse, clone 4D5, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, rat
应用
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-RUNX2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0232, purified immunoglobulin, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
ANTI-RUNX2 antibody produced in mouse, clone 4E5, ascites fluid,
物种反应性
human
应用
ELISA
western blot
Monoclonal Anti-RUNX2 antibody produced in mouse, clone 1D8, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence

immunohistochemistry

western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human RUNX2,
物种
human