跳转至内容
Merck

NF2

neurofibromin 2 (merlin)

别名:
ACN, BANF, SCH
物种:
UniProtKB ID:
基因ID:
  • Human(4771) Summary: This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. [provided by RefSeq, Jul 2008]
  • Mouse(18016) neurofibromatosis 2
  • Rat(25744) neurofibromin 2 (merlin)
  • chicken(395158) neurofibromin 2 (bilateral acoustic neuroma)
  • dog(477535) neurofibromin 2 (merlin)
  • domestic cat(101087787) neurofibromin 2 (merlin)
  • cow(540479) neurofibromin 2 (merlin)
  • Horse(100058977) neurofibromin 2 (merlin)
  • Domestic Rabbit(100357691) neurofibromin 2 (merlin)
  • naked mole-rat(101706100) neurofibromin 2 (merlin)
  • domestic guinea pig(100715365) neurofibromin 2 (merlin)
  • sheep(101107995) neurofibromin 2 (merlin)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
抗-NF2 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
Anti-Merlin (NF2) Antibody, clone 1C4, clone 1C4, from mouse,
物种反应性
human, mouse, rat
应用
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-NF2 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Anti-phospho-Merlin (pSer10) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry

western blot
ANTI-MERLIN(N-TERMINAL) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human NF2,
物种
human