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Merck

NCOR2

nuclear receptor corepressor 2

别名:
CTG26, N-CoR2, SMAP270, SMRT, SMRTE, SMRTE-tau, TNRC14, TRAC, TRAC-1, TRAC1
物种:
UniProtKB ID:
基因ID:
  • Human(9612) Summary: This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011]
  • Mouse(20602) nuclear receptor co-repressor 2
  • Rat(360801) nuclear receptor co-repressor 2
  • Zebrafish(561503) nuclear receptor co-repressor 2
  • chicken(416815) nuclear receptor corepressor 2
  • cow(538549) nuclear receptor corepressor 2
  • Horse(100059253) nuclear receptor corepressor 2
  • domestic cat(101083973) nuclear receptor corepressor 2
  • dog(486242) nuclear receptor corepressor 2
  • domestic guinea pig(100720194) nuclear receptor corepressor 2
  • naked mole-rat(101702626) nuclear receptor corepressor 2
  • sheep(101121042) nuclear receptor corepressor 2

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Antibodies

货号
说明
物种反应性
应用
Anti-NCOR2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence

immunohistochemistry
Anti-SMRTe Antibody, Upstate®, from rabbit,
物种反应性
human
应用
ChIP
immunocytochemistry

western blot
ChIPAb+ SMRT - ChIP Validated Antibody and Primer Set, ascites fluid, from mouse,
物种反应性
human, mouse, rat
应用
ChIP
electrophoretic mobility shift assay

immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-SMRT Antibody, clone 1SM-1E7, ascites fluid, clone 1SM-1E7, from mouse,
物种反应性
human, mouse, rat
应用
western blot

Proteins

货号
说明
物种
NCOR2/SMRT human, recombinant, expressed in E. coli, ≥60% (SDS-PAGE),
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human NCOR2,
物种
human