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Merck

MCM2

minichromosome maintenance complex component 2

别名:
BM28, CCNL1, CDCL1, D3S3194, MITOTIN, cdc19
物种:
UniProtKB ID:
基因ID:
  • Human(4171) Summary: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
  • Mouse(17216) minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
  • Rat(312538) minichromosome maintenance complex component 2
  • domestic guinea pig(100722936) minichromosome maintenance complex component 2
  • naked mole-rat(101710978) minichromosome maintenance complex component 2
  • sheep(101116097) minichromosome maintenance complex component 2
  • Zebrafish(192338) MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae)
  • domestic cat(101090176) minichromosome maintenance complex component 2
  • dog(484622) minichromosome maintenance complex component 2
  • cow(510120) minichromosome maintenance complex component 2
  • chicken(416027) minichromosome maintenance complex component 2
  • Thale Cress(841056) minichromosome maintenance protein 2
  • fruit fly(40973) Minichromosome maintenance 2

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Antibodies

货号
说明
物种反应性
应用
Rabbit anti-Phospho MCM2 (S108) Antibody, Affinity Purified, ,
物种反应性
human, mouse
应用
immunohistochemistry
western blot
Rabbit anti-MCM2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
物种反应性
human, mouse
应用
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-MCM2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Anti-MCM2 antibody, Rabbit monoclonal, clone SP85, recombinant, expressed in proprietary host, affinity isolated antibody,
物种反应性
bovine, dog, frog, human, mouse, rat
应用
flow cytometry
immunohistochemistry

western blot
Anti-MCM2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human MCM2,
物种
human
MISSION® esiRNA, targeting mouse Mcm2,
物种
mouse