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Merck

IMPDH1

IMP (inosine 5'-monophosphate) dehydrogenase 1

别名:
IMPD, IMPD1, LCA11, RP10, sWSS2608
物种:
UniProtKB ID:
基因ID:
  • Human(3614) Summary: The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
  • Mouse(23917) inosine 5'-phosphate dehydrogenase 1
  • Rat(362329) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • sheep(101104144) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • Domestic Rabbit(100357217) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • domestic guinea pig(100717020) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • naked mole-rat(101720344) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • cow(504305) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • domestic cat(101084274) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • Horse(100071737) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • dog(608783) IMP (inosine 5'-monophosphate) dehydrogenase 1

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Antibodies

货号
说明
物种反应性
应用
Monoclonal Anti-IMPDH1 antibody produced in mouse, clone 3G6, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Anti-IMPDH1 Antibody, clone 4F9.1, clone 4F9.1, from mouse,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Anti-IMPDH1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
immunohistochemistry
western blot
Anti-IMPDH1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot

Small Molecule - Inhibitor

货号
说明
物种
利巴韦林, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
利巴韦林, United States Pharmacopeia (USP) Reference Standard,
物种
human
利巴韦林, European Pharmacopoeia (EP) Reference Standard,
物种
human
利巴韦林杂质标准品, British Pharmacopoeia (BP) Reference Standard,
物种
human
利巴韦林, British Pharmacopoeia (BP) Reference Standard,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Impdh1,
物种
mouse
MISSION® esiRNA, targeting human IMPDH1,
物种
human