跳转至内容
Merck

IDH3B

isocitrate dehydrogenase 3 (NAD+) beta

别名:
H-IDHB, RP46
物种:
UniProtKB ID:
基因ID:
  • Human(3420) Summary: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(170718) isocitrate dehydrogenase 3 (NAD+) beta
  • Rat(94173) isocitrate dehydrogenase 3 (NAD+) beta
  • Zebrafish(415247) isocitrate dehydrogenase 3 (NAD+) beta
  • chicken(426573) isocitrate dehydrogenase 3 (NAD+) beta
  • dog(477177) isocitrate dehydrogenase 3 (NAD+) beta
  • cow(613338) isocitrate dehydrogenase 3 (NAD+) beta
  • domestic cat(101099035) isocitrate dehydrogenase 3 (NAD+) beta
  • domestic guinea pig(100717400) isocitrate dehydrogenase 3 (NAD+) beta
  • naked mole-rat(101709094) isocitrate dehydrogenase 3 (NAD+) beta
  • sheep(101104080) isocitrate dehydrogenase 3 (NAD+) beta

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
Anti-IDH3B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Anti-IDH3B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
western blot
Anti-IDH3B antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Monoclonal Anti-IDH3B antibody produced in mouse, clone 3A10, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA

Kits

货号
说明
物种
IDH 活性检测试剂盒, sufficient for 100 colorimetric tests,
物种
mouse, rat, human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Idh3b,
物种
mouse