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Merck

GPX1

glutathione peroxidase 1

别名:
GPXD, GSHPX1
物种:
UniProtKB ID:
基因ID:
  • Human(2876) Summary: This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14775) glutathione peroxidase 1
  • Rat(24404) glutathione peroxidase 1
  • Thale Cress(817046) phospholipid hydroperoxide glutathione peroxidase 1
  • chicken(100857115) glutathione peroxidase 1
  • domestic cat(101083751) glutathione peroxidase 1
  • cow(281209) glutathione peroxidase 1
  • Horse(100053396) glutathione peroxidase 1
  • dog(442961) glutathione peroxidase 1
  • sheep(100820742) glutathione peroxidase 1
  • Domestic Rabbit(100009258) glutathione peroxidase 1
  • domestic guinea pig(100729115) glutathione peroxidase 1
  • naked mole-rat(101710466) glutathione peroxidase 1

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Antibodies

货号
说明
物种反应性
应用
Anti-GPX1 Antibody, clone 1J19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
canine, feline, human, monkey, porcine
应用
immunocytochemistry
immunohistochemistry

western blot
单克隆抗-FLAG® M2-过氧化物酶(HRP) 小鼠抗, clone M2, purified immunoglobulin, buffered aqueous glycerol solution,
物种反应性
all
应用
ELISA
抗 GPX1 兔抗, affinity isolated antibody, buffered aqueous solution,
物种反应性
alligator, human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
Anti-Glutathione peroxidase 1 (ISO1) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, pig
应用
ELISA
immunohistochemistry

western blot
Anti-Gpx1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
bovine, mouse, rat
应用
ELISA
western blot

Proteins

货号
说明
物种
GPX1 human, recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE),
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human GPX1,
物种
human