SML0154

SPV-106

≥98% (HPLC)

• Synonym(s): 2-Pentadecylidene-Propanedioic acid 1,3-diethyl ester, Pentadecylidenemalonate 1b
• Empirical Formula (Hill Notation): C₂₂H₄₀O₄
• CAS Number: 1036939-38-4
• Molecular Weight: 368.55
• MDL number: MFCD20527327
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825202
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: oil
• color: colorless
• storage temp.: 2-8°C
• SMILES string: CCCCCCCCCCCCCC\C=C(\C(=O)OCC)C(=O)OCC
• InChI: 1S/C22H40O4/c1-4-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21(23)25-5-2)22(24)26-6-3/h19H,4-18H2,1-3H3
• InChI key: APIJHPAXMCKJBY-UHFFFAOYSA-N

Description

Biochem/physiol Actions

SPV106 is a mixed inhibitor/activator of histone acetyltransferase (HAT) activity. The compound inhibits the activity of p300/CBP, but potentiates p300/CBP-associated factor (PCAF) activity. SPV106 also induces S-phase cell cycle arrest and apoptosis in U937 cells.

Features and Benefits

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Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H317
• Precautionary Statements: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable