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Merck

WDR35

WD repeat domain 35

Synonyms:
CED2, IFT121
Species:
UniProtKB ID:
Gene ID:
  • Human(57539) Summary: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Two patients with Sensenbrenner syndrome / cranioectodermal dysplasia (CED) were identified with mutations in this gene, consistent with a possible ciliary function.[provided by RefSeq, Sep 2010]
  • Mouse(74682) WD repeat domain 35
  • Rat(298876) WD repeat domain 35
  • Zebrafish(565515) WD repeat domain 35
  • chicken(421958) WD repeat domain 35
  • dog(475677) WD repeat domain 35
  • domestic guinea pig(100723470) WD repeat domain 35
  • naked mole-rat(101721184) WD repeat domain 35
  • cow(100337107) WD repeat domain 35
  • sheep(101103137) WD repeat domain 35

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-WDR35 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Wdr35,
Species
mouse
MISSION® esiRNA, targeting human WDR35,
Species
human