QPRT
quinolinate phosphoribosyltransferase
Synonyms:
QPRTase
Species:
Human QPRT (23475), Mouse Qprt (67375), Rat Qprt (293504), dog QPRT (607664), domestic cat QPRT (101087441), domestic guinea pig Qprt (100727900), naked mole-rat Qprt (101718250), cow QPRT (614254), Goat QPRT (100861315), sheep QPRT (101102696)
UniProtKB ID:
Gene ID:
- Human(23475) Summary: This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq, Jul 2008]
- Mouse(67375) quinolinate phosphoribosyltransferase
- Rat(293504) quinolinate phosphoribosyltransferase
- dog(607664) quinolinate phosphoribosyltransferase
- domestic cat(101087441) quinolinate phosphoribosyltransferase
- domestic guinea pig(100727900) quinolinate phosphoribosyltransferase
- naked mole-rat(101718250) quinolinate phosphoribosyltransferase
- cow(614254) quinolinate phosphoribosyltransferase
- Goat(100861315) quinolinate phosphoribosyltransferase
- sheep(101102696) quinolinate phosphoribosyltransferase
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-QPRT antibody produced in mouse, clone 5D11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-QPRT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
western blot
Anti-QPRT antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-QPRT antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-QPRT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
esiRNA
Product Number
Description
Species