PDHB
pyruvate dehydrogenase (lipoamide) beta
Synonyms:
PDHBD, PDHE1-B, PHE1B
Species:
Human PDHB (5162), Mouse Pdhb (68263), Rat Pdhb (289950), cow PDHB (613610), sheep PDHB (101121975), domestic guinea pig Pdhb (100733476), naked mole-rat Pdhb (101714134), Zebrafish pdhb (406428), Horse PDHB (100050581), domestic cat PDHB (101100374) ...More
UniProtKB ID:
Gene ID:
- Human(5162) Summary: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012]
- Mouse(68263) pyruvate dehydrogenase (lipoamide) beta
- Rat(289950) pyruvate dehydrogenase (lipoamide) beta
- cow(613610) pyruvate dehydrogenase (lipoamide) beta
- sheep(101121975) pyruvate dehydrogenase (lipoamide) beta
- domestic guinea pig(100733476) pyruvate dehydrogenase (lipoamide) beta
- naked mole-rat(101714134) pyruvate dehydrogenase (lipoamide) beta
- Zebrafish(406428) pyruvate dehydrogenase (lipoamide) beta
- Horse(100050581) pyruvate dehydrogenase (lipoamide) beta
- domestic cat(101100374) pyruvate dehydrogenase (lipoamide) beta
- dog(476574) pyruvate dehydrogenase (lipoamide) beta
- chicken(416066) pyruvate dehydrogenase (lipoamide) beta
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-PDHB antibody produced in mouse, clone 1D1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-PDHB antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Anti-PDHB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-PDHB antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-PDHB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Kits
Product Number
Description
Species
Pyruvate Dehydrogenase Activity Assay Kit, sufficient for 100 colorimetric tests,
Species
rat, mouse, human