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Merck

ITGB3

integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)

Synonyms:
BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT
Species:
UniProtKB ID:
Gene ID:
  • Human(3690) Summary: The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008]
  • Mouse(16416) integrin beta 3
  • Rat(29302) integrin, beta 3
  • sheep(100423047) integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • domestic guinea pig(100731365) integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • naked mole-rat(101715910) integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • chicken(374209) integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • domestic cat(101092159) integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • cow(282642) integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • Horse(100009709) integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • dog(403788) integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)

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Small Molecule - Antagonist

Product Number
Description
Species
Gly-Arg-Gly-Asp-Ser, ≥97% (HPLC),
Species
human
Arg-Gly-Asp-Ser, ≥95% (HPLC),
Species
mouse, human
Acetylsalicylic acid, ≥99.0%,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Integrin β3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-ITGB3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Integrin beta-3 (CD61) Antibody, clone HMb3-1, clone HMb3-1, from hamster(Armenian),
Species Reactivity
mouse
Application
flow cytometry
immunohistochemistry
Anti-Integrin β3 (CD61) Antibody, clone SAP, clone SAP, Upstate®, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-Integrin β3 Antibody, clone BB10, clone BB10, Chemicon®, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Tirofiban, ≥98.5% (HPLC),
Species
human
Tirofiban hydrochloride monohydrate, ≥98% (HPLC),
Species
human
Acetylsalicylic acid, ≥99.0%,
Species
human

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
Arg-Gly-Asp-Ser, ≥95% (HPLC),
Species
mouse, human
Acetylsalicylic acid, ≥99.0%,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Itgb3,
Species
mouse
MISSION® esiRNA, targeting human ITGB3, RP11-290H9.2,
Species
human