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Merck

F9

coagulation factor IX

Synonyms:
FIX, HEMB, P19, PTC, THPH8
Species:
UniProtKB ID:
Gene ID:
  • Human(2158) Summary: This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. [provided by RefSeq, Jul 2008]
  • Mouse(14071) coagulation factor IX
  • Rat(24946) coagulation factor IX
  • chicken(374258) coagulation factor IX
  • dog(404015) coagulation factor IX
  • domestic cat(493973) coagulation factor IX
  • cow(280688) coagulation factor IX
  • Horse(100054449) coagulation factor IX
  • domestic guinea pig(100135464) coagulation factor IX
  • naked mole-rat(101724977) coagulation factor IX
  • sheep(443316) coagulation factor IX
  • Domestic Rabbit(100009113) coagulation factor IX

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Factor IX antibody, Mouse monoclonal, clone HIX-1, purified from hybridma cell culture,
Species Reactivity
human
Application
ELISA
western blot
Anti-Factor IX antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
dot blot

western blot
Anti-Factor IX antibody, Mouse monoclonal, clone HIX-5, purified from hybridoma cell culture,
Species Reactivity
human
Application
ELISA
western blot

Proteins

Product Number
Description
Species
Factor IX human, aqueous glycerol solution, ≥145 units/mg protein,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human F9,
Species
human