L1417

15(S)-Latanoprost solution

≥95%

• Synonym(s): (5Z,9α,11α,15S)-9,11,15-Trihydroxy-17-phenyl-18,19,20-trinor-prost-5-en-1-oate isopropyl ester
• Empirical Formula (Hill Notation): C₂₆H₄₀O₅
• Molecular Weight: 432.59
• EC Number: 201-185-2
• MDL number: MFCD04974500
• UNSPSC Code: 12352200
• PubChem Substance ID: 329817389
• NACRES: NA.77

Properties

• Quality Level: 200
• Assay: ≥95%
• form: liquid
• concentration: 10 mg/mL in methyl acetate
• storage temp.: −20°C
• SMILES string: CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1CC[C@H](O)CCc2ccccc2
• InChI: 1S/C26H40O5/c1-19(2)31-26(30)13-9-4-3-8-12-22-23(25(29)18-24(22)28)17-16-21(27)15-14-20-10-6-5-7-11-20/h3,5-8,10-11,19,21-25,27-29H,4,9,12-18H2,1-2H3/b8-3-/t21-,22-,23-,24+,25-/m1/s1
• InChI key: GGXICVAJURFBLW-SCTZCWPJSA-N

Description

Linkage

15(S)-Latanoprost is the less active C-15 isomer of latanoprost where the C-15 hydroxyl group is inverted relative to its natural (α) position in a prostaglandin such as PGF_2α. The 15(S)-isomer of latanoprost occurs as an impurity of between 0.1 and 1% in most commercial preparations of latanoprost.

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H319,H336
• Precautionary Statements: P210 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Target Organs: Central nervous system
• Supplementary Hazards: EUH066
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 3.2 °F - closed cup
• Flash Point(C): -16 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves