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I0627

Supelco

Isobarbituric acid

analytical standard

Synonym(s):

2,4,5-Trihydroxypyrimidine, 5-Hydroxyuracil

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About This Item

Empirical Formula (Hill Notation):
C4H4N2O3
CAS Number:
496-76-4
Molecular Weight:
128.09
Beilstein:
127205
EC Number:
207-829-9
MDL number:
MFCD00082987
UNSPSC Code:
41116107
PubChem Substance ID:
329815320
NACRES:
NA.24
Pricing and availability is not currently available.

grade

analytical standard

Quality Level

100

Assay

~98%

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

>300 °C (dec.) (lit.)

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

O=C1CNC(=O)NC1=O

InChI

1S/C4H4N2O3/c7-2-1-5-4(9)6-3(2)8/h1H2,(H2,5,6,8,9)

InChI key

FQXOOGHQVPKHPG-UHFFFAOYSA-N

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Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

application(s)

environmental
food and beverages, microbiology

application(s)

microbiology

application(s)

environmental
microbiology

application(s)

environmental
microbiology

technique(s)

microbe id | in situ hybriziation: suitable

technique(s)

-

technique(s)

microbe id | in situ hybriziation: suitable

technique(s)

microbe id | in situ hybriziation: suitable

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Certificates of Analysis (COA)

    Lot/Batch Number
    STBK5580
    STBJ8650
    STBH7050
    STBG9194
    STBF8677V

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    Grégory Eot-Houllier et al.
    Nucleic acids research, 35(10), 3355-3366 (2007-05-01)
    Evidence has emerged that repair of clustered DNA lesions may be compromised, possibly leading to the formation of double-strand breaks (DSB) and, thus, to deleterious events. The first repair event occurring at a multiply damaged site (MDS) is of major
    Zuzanna Bukowy et al.
    Nucleic acids research, 36(15), 4975-4987 (2008-07-29)
    Werner syndrome (WS) is a premature aging disorder caused by mutations in the WS gene (WRN). Although WRN has been suggested to play an important role in DNA metabolic pathways, such as recombination, replication and repair, its precise role still
    Jason L Parsons et al.
    Nucleic acids research, 33(15), 4849-4856 (2005-09-01)
    Base excision repair is the major pathway for the repair of oxidative DNA damage in human cells that is initiated by a damage-specific DNA glycosylase. In human cells, the major DNA glycosylases for the excision of oxidative base damage are
    Grégory Eot-Houllier et al.
    Nucleic acids research, 33(1), 260-271 (2005-01-14)
    Clustered DNA lesions, possibly induced by ionizing radiation, constitute a trial for repair processes. Indeed, recent studies suggest that repair of such lesions may be compromised, potentially leading to the formation of lethal double-strand breaks (DSBs). A complex multiply damaged
    Gunn A Hildrestrand et al.
    Experimental cell research, 315(15), 2558-2567 (2009-05-30)
    Adipose-tissue derived mesenchymal stem cells (AT-MSCs) are a promising tool for use in cell-based therapies. However, in vitro expansion is required to obtain clinically relevant cell numbers, and this might increase the chance of genomic instability. DNA repair is crucial
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