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432199

Sigma-Aldrich

Leucoberbelin Blue I

Dye content 65 %

Synonym(s):

LBB

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About This Item

Empirical Formula (Hill Notation):
C23H26N2O3S
CAS Number:
52748-86-4
Molecular Weight:
410.53
MDL number:
MFCD00217522
UNSPSC Code:
12171500
PubChem Substance ID:
24867076
NACRES:
NA.47

form

powder

composition

Dye content, 65%

mp

>300 °C (lit.)

solubility

water: 50 g/L

λmax

253 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

CN(C)c1ccc(cc1)C(c2ccc(cc2)N(C)C)c3ccccc3S(O)(=O)=O

InChI

1S/C23H26N2O3S/c1-24(2)19-13-9-17(10-14-19)23(18-11-15-20(16-12-18)25(3)4)21-7-5-6-8-22(21)29(26,27)28/h5-16,23H,1-4H3,(H,26,27,28)

InChI key

MCKLFIWDQVFMEK-UHFFFAOYSA-N

General description

Leucoberbelin Blue I is a colorimetric reagent redox dye. It is a water-soluble leuco base also abbreviated as LBB. Upon oxidation, LBB forms a colored complex which is stoichiometrically related to the oxidation state of the reagent.

Application

Leucoberbelin blue I has been used as a quencher in the time-resolved fluorescence QRET technique for receptor-ligand interaction screening. LBB assay is used to indicate the kinetics of Mn (II) oxides formation.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Deric R Learman et al.
Frontiers in microbiology, 4, 262-262 (2013-09-13)
Manganese (Mn) oxides are among the most reactive sorbents and oxidants within the environment, where they play a central role in the cycling of nutrients, metals, and carbon. Recent discoveries have identified superoxide ([Formula: see text]) both of biogenic and
Natália R Barboza et al.
Frontiers in microbiology, 8, 1946-1946 (2017-10-25)
Manganese is an important metal for the maintenance of several biological functions, but it can be toxic in high concentrations. One of the main forms of human exposure to metals, such as manganese (Mn), is the consumption of solar salt
Carolyn A Zeiner et al.
Frontiers in microbiology, 12, 610497-610497 (2021-03-02)
Manganese (Mn) oxides are among the strongest oxidants and sorbents in the environment, and Mn(II) oxidation to Mn(III/IV) (hydr)oxides includes both abiotic and microbially-mediated processes. While white-rot Basidiomycete fungi oxidize Mn(II) using laccases and manganese peroxidases in association with lignocellulose
Dilara Islam et al.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 122(6), 463-475 (2013-09-14)
Shigellosis is a worldwide disease, characterized by abdominal pain, fever, vomiting, and the passage of blood- and mucus-streaked stools. Rhesus monkeys and other primates are the only animals that are naturally susceptible to shigellosis. A suitable animal model is required
Matthew R Jones et al.
Talanta, 200, 91-99 (2019-05-01)
In terms of its oxidative strength, the MnO2/Mn2+ couple is one of the strongest in the aquatic environment. The intermediate oxidation state, manganese(III), is stabilized by a range of organic ligands (Mn(III)-L) and some of these complexes are also strong
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