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form
liquid
concentration
10-20 wt. % in ethanol
refractive index
n20/D 1.36
density
0.792 g/mL at 25 °C
storage temp.
2-8°C
SMILES string
CCON=O
InChI
1S/C2H5NO2/c1-2-5-3-4/h2H2,1H3
InChI key
QQZWEECEMNQSTG-UHFFFAOYSA-N
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General description
The reactions of ethyl nitrite solution with human haemoglobin and sperm whale myoglobin were studied.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2
Storage Class Code
3 - Flammable liquids
WGK
WGK 1
Flash Point(F)
59.0 °F - closed cup
Flash Point(C)
15 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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The Journal of biological chemistry, 256(23), 12399-12404 (1981-12-10)
The reactions of human hemoglobin and sperm whale myoglobin with ethyl nitrite under aerobic conditions have been examined in kinetic detail. Ethyl nitrite converts two equivalents of oxyhemoglobin or oxymyoglobin to their oxidized counterparts with concurrent production of one equivalent
Journal of reconstructive microsurgery, 23(5), 257-262 (2007-09-19)
Vasospasm leading to thrombosis is a major cause of free flap failure. Flap blood flow may improve by application of vasodilating agents to the pedicle. The purpose of this study is to evaluate the effect of a novel S-nitrosylating agent
Annals of surgery, 257(5), 971-977 (2013-01-31)
To determine if reduction in nitric oxide bioactivity contributes to the physiological instability that occurs after brain death and, if so, to also determine in this setting whether administration of a renitrosylating agent could improve systemic physiological status. Organ function
Inhaled ethyl nitrite gas for persistent pulmonary hypertension in infants.
Lancet (London, England), 360(9350), 2076-2077 (2002-12-31)
Clinical and translational science, 2(6), 405-412 (2010-05-07)
A method to maintain organ blood flow during laparoscopic surgery has not been developed. Here we determined if ethyl nitrite, an S-nitrosylating agent that would maintain nitric oxide bioactivity (the major regulator of tissue perfusion), might be an effective intervention
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