PRICKLE1
prickle homolog 1 (Drosophila)
EPM1B, RILP
Human PRICKLE1 (144165), Mouse Prickle1 (106042), Rat Prickle1 (315259), cow PRICKLE1 (785152), sheep PRICKLE1 (101115695), naked mole-rat Prickle1 (101700621), domestic guinea pig Prickle1 (100715344), chicken PRICKLE1 (417793), dog PRICKLE1 (477638), domestic cat PRICKLE1 (101098966)
- Human(144165) Summary: This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Sep 2009]
- Mouse(106042) prickle homolog 1 (Drosophila)
- Rat(315259) prickle homolog 1 (Drosophila)
- cow(785152) prickle homolog 1 (Drosophila)
- sheep(101115695) prickle homolog 1 (Drosophila)
- naked mole-rat(101700621) prickle homolog 1 (Drosophila)
- domestic guinea pig(100715344) prickle homolog 1 (Drosophila)
- chicken(417793) prickle homolog 1 (Drosophila)
- dog(477638) prickle homolog 1 (Drosophila)
- domestic cat(101098966) prickle homolog 1 (Drosophila)
- Horse(100050052) prickle homolog 1 (Drosophila)
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Antibodies
Anti-PRICKLE1 antibody produced in rabbit, affinity isolated antibody,
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immunofluorescence
western blot