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Merck

CA4

carbonic anhydrase IV

Synonyms:
CAIV, Car4, RP17
Species:
UniProtKB ID:
Gene ID:
  • Human(762) Summary: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known; however, it may have a role in inherited renal abnormalities of bicarbonate transport. [provided by RefSeq, Jul 2008]
  • chicken(417647) carbonic anhydrase IV
  • dog(480591) carbonic anhydrase IV
  • domestic cat(101088531) carbonic anhydrase IV
  • cow(280741) carbonic anhydrase IV
  • sheep(101109718) carbonic anhydrase IV
  • Domestic Rabbit(100009226) carbonic anhydrase IV
  • domestic guinea pig(100731463) carbonic anhydrase IV
  • naked mole-rat(101700918) carbonic anhydrase IV

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ELISA

Product Number
Description
Species
Human CA4 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Small Molecule - Activator

Product Number
Description
Species
L-Phenylalanine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%,
Species
human
L-Phenylalanine, reagent grade, ≥98%,
Species
human
L-Phenylalanine, BioUltra, ≥99.0% (NT),
Species
human
D-Phenylalanine, ≥98% (HPLC),
Species
human
Topiramate, ≥98% (HPLC), solid,
Species
human, mouse, rat

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CA4 antibody produced in mouse, clone 4G6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-CA4 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-CA4 (AB1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-CA4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-CA4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

Small Molecule - Inhibitor

Product Number
Description
Species
Chlorothiazide, thiazide diuretic,
Species
human
Methazolamide, United States Pharmacopeia (USP) Reference Standard,
Species
human
Methazolamide, ≥98% (HPLC),
Species
human
Acetazolamide, British Pharmacopoeia (BP) Reference Standard,
Species
human
Acetazolamide, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

Proteins

Product Number
Description
Species
Carbonic Anhydrase 4/CA4 human, recombinant, expressed in HEK 293 cells, ≥92% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CA4,
Species
human